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Aggregation Analysis System

Wed, 01/22/2014 - 9:55am

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Shimadzu Scientific Instruments has introduced the Aggregates Sizer Aggregation Analysis System, which offers the first effective quantitative, high-speed evaluation of 100 nm to 10μm SVP aggregates that may be present in biopharmaceuticals. This system is capable of covering all ranges of SVP particle size in a single measurement and can evaluate the concentration (μg/mL) that can induce allergic systemic reactions such as anaphylaxis and other severe side effects. By enabling screening for and elimination of aggregation prone-proteins in the early stages of drug development, the Aggregates Sizer will save time and reduce costs. It also features greater sensitivity and speed and is capable of accurately measuring micro sample quantities using disposable cells for 0.4 mL sample quantities. Size and quantity changes can be confirmed quantitatively as a concentration (unit: μg/mL) at one-second intervals, allowing real-time evaluation of rates of change and observation of aggregation processes as samples are mechanically stimulated.

 

Shimadzu Scientific Instruments (SSI)  

www.ssi.shimadzu.com 

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