The DRYPOUR packaging system from EMD Millipore minimizes caking of hygroscopic salts used in pharmaceutical manufacturing during transport and storage. The system, which consists of a polyethylene drum with a tamper-evident seal, a polyethylene liner with integrated desiccant bags and a breathable interior Tyvek liner, helps improve operational efficiency by reducing the time and effort needed to break up heavily caked raw materials. Any water vapor in the product itself can permeate the interior, tear-resistant liner, migrate into the outer polyethylene liner and be absorbed by the integrated desiccant. The desiccant bags in the DRYPOUR system are fixed to the perforated polyethylene liner, thus preventing contact with the product, so product quality is not compromised. For maximum effect, the desiccant bags are mounted in varying places on the liner. The system is available in 100 kilogram package sizes and can be moved with common handling devices. The system meets both European Pharmacopoeia and USP requirements.