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KEY WEST, Florida (Reuters) - Tropical Storm Isaac lashed south Florida with winds and heavy rain on Sunday after battering the Caribbean, threatening to interrupt most U.S. offshore oil production in the Gulf of Mexico and disrupting plans for the Republican National Convention in Tampa.

Isaac is expected to strengthen to a Category 2 hurricane and hit the Gulf Coast somewhere between Florida and Louisiana at midweek - on or near the seventh anniversary of Hurricane Katrina - the U.S. National Hurricane Center (NHC) said in an advisory.

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