The Cosmetic, Toiletry and Fragrance Association (CTFA) has filed comprehensive comments with the FDA on the science and regulation of nanoparticles in personal care products. The comments address issues raised in a petition filed with the FDA earlier this year on the use of nanotechnology in personal care products in particular, sunscreens. Previously, the FDA had concluded that the nanoparticles used in sunscreens, titanium dioxide and zinc oxide, are safe for use in personal care products. Titanium dioxide had been approved for use as a color additive in food as well as for drugs, cosmetics and contact lenses. Zinc oxide had been approved for use as a food ingredient, a color additive in drugs and cosmetics and as a protectant for injured skin. "Nanoparticle ingredients in personal care products sit on top of the skin, are used in small amounts and are not absorbed into the body. The general scientific consensus is that there is no risk to human health," says John Bailey, executive vice president for science at CTFA and a former FDA official.