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Around the World with AMRI, Part 4

Wed, 10/03/2012 - 12:21pm
MIKE AUERBACK, Editor-in-Chief, Pharmaceutical Processing

This is part four of a five-part piece. Part one can be found here. Part two can be found here. Part three can be found here.

AMRI_2Pilot Plant Facility

Classified by type and production capacity, the Rensselaer site offers the following capabilities and equipment:

  1. Four production suites using an open plan, multi-purpose reaction train system.
  2. 50- to 300-gallon glass-lined and Hastelloy reactor trains.
  3. Multi-functional filtration/dryer technology capabilities.
  4. A typical production scale from 5 to 100 kg.

“The pilot plant facility is an open-concept facility,” says Saffee. “We can mix and match equipment, and run chemistry across all of them.”

AMRI boasts three high-potency (HP) compound production suites all in a state-of-the art facility. “This is one of the outstanding capabilities that this site has,” says Saffee. “The ability to start at grams and move up to higher quantities – our customers tell us that rarely can they find a CMO that has this capacity and capability.”

Each of the below HP production suites include the following:

Small-Scale Suite

  1. A Howorth Technologies 3.8 m3 isolator.
  2. A total containment for glass reactors up to 25 L.
  3. A typical production scale from 25 g to 2 kg.

Mid-Scale Suite

  1. A Flanders 1.74 m3 isolator.
  2. Walk-in laminar fume hoods with 50- to 400-L glass and Hastelloy reactors.
  3. A typical production scale from 1 to 40 kg.

Large-Scale Suite

  1. Howorth Technologies isolators.
  2. Up to two Hastelloy 1,200-L reactors.
  3. A typical production scale from 3 to 120 kg.
  4. Plug-and-play services and overhead connectivity for rapid re-configuration of equipment trains.

Please tune into tomorrow’s Chemical Equipment Daily for part five of this five-part series. To read part one of this five-part series, please click here. To read part two of this five-part series, please click here. To read part three of this five-part series, please click here. 

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